Chem-mist 2F-DCK Spray 10% (2-Fluorodeschloroketamine HCl)
The Chem-mist 2F-DCK spray 10% is a specialized liquid reference material formulated for forensic toxicology laboratories and analytical chemists profiling arylcyclohexylamine dissociatives. Containing exactly 1000 mg of 2-fluorodeschloroketamine hydrochloride (CAS 111982-49-1) in a 10 mL precision pump, the Chem-mist 2F-DCK spray 10% delivers a 10% w/v concentration designed for rapid, reproducible volumetric calibration of GC-MS and LC-MS/MS instrumentation.
Each metered actuation of the Chem-mist 2F-DCK spray 10% dispenses a consistent 14 mg aliquot. This eliminates the weighing errors associated with hygroscopic crystalline powders, allowing QA managers to prepare working stock solutions traceably. A standard unit yields over 70 actuations, making the Chem-mist 2F-DCK spray 10% an efficient choice for high-throughput screening programs requiring lot-to-lot consistency.
Chemical Specifications & Arylcyclohexylamine Profiling
2F-DCK belongs to the arylcyclohexylamine class, sharing structural homology with ketamine and deschloroketamine while carrying a fluorine substitution at the 2-position of the phenyl ring. That modification shifts both chromatographic retention and mass spectral fragmentation, which is why dedicated reference material is required for confident identification. Every batch of Chem-mist 2F-DCK spray 10% ships with HPLC purity verification, NMR scaffold confirmation, and HRMS exact-mass documentation.
| Product Name | 2F-DCK HCl 10% w/v Calibrated Spray (Chem-mist format) |
|---|---|
| Synonym | 2-Fluorodeschloroketamine HCl |
| CAS Number | 111982-49-1 |
| Molecular Formula | C13H16FNO · HCl |
| Molar Mass | 257.7 g/mol |
| Concentration | 10% w/v (100 mg/mL) |
| Purity | >98% (HPLC/NMR verified) |
| Format | 10 mL precision pump (~1,000 mg total active, ~70 actuations) |
Volumetric Precision for Calibration
Crystalline arylcyclohexylamine salts are hygroscopic and electrostatic, introducing weighing drift during calibrator preparation. The metered pump of the Chem-mist 2F-DCK spray 10% eliminates both variables: analysts dispense by actuation count rather than balance reading, then dilute to volume in certified solvent. This volumetric workflow shortens preparation time, reduces exposure events, and produces calibration curves with tighter residuals across replicate runs.
Furthermore, the liquid matrix ensures complete solubility upon dispensing, bypassing the sonication and vortexing steps required for dry powder dissolution. This accelerates the daily calibration workflow significantly, allowing technicians to process larger batches of quality control samples before instrument run times begin.
Analytical Applications in Forensic Toxicology
Laboratories deploying the Chem-mist 2F-DCK spray 10% can spike blank urine, blood, and oral-fluid matrices for limit-of-detection studies, solid-phase extraction recovery testing, and ketamine-analog screening panels. The liquid standard also supports DUID casework method development and post-mortem redistribution studies where novel dissociatives increasingly appear alongside legacy anesthetics. When your laboratory requires a reliable Chem-mist 2F-DCK spray 10%, ChemNexis Pharma ensures every unit is matched to its batch-specific Certificate of Analysis — explore the full research chemical catalog for companion standards.
By utilizing a pre-dissolved 10% w/v format, laboratories can easily perform serial dilutions to reach the low ng/mL thresholds required for modern triple-quadrupole mass spectrometers. This is particularly critical when validating new solid-phase extraction cartridges or testing novel polymer-based sorbents designed to isolate highly lipophilic dissociatives from complex post-mortem central blood matrices.
Quality Assurance, Storage & Stability
To preserve the >98% purity baseline, the Chem-mist 2F-DCK spray 10% is packaged in light-resistant amber glass with an inert-headspace pump assembly that prevents oxidative degradation of the fluorophenyl moiety. Storage protocols specify a cool, dark, desiccated environment (2–8 °C preferred); under these conditions the certified concentration remains stable for a minimum of 24 months, protecting long-term inventory value for high-volume forensic programs.
Occupational Safety & Handling Protocols
As a concentrated liquid solution, handling requires standard laboratory PPE — nitrile gloves, lab coat, and safety goggles — with all aliquoting performed inside a certified fume hood.
- Inhalation: aerosolized solvent can cause respiratory irritation; use local exhaust ventilation.
- Skin/Eye Contact: flush immediately with copious water for 15 minutes.
- Environmental: never discharge to municipal water; dispose via licensed hazardous-waste contractors.
These controls keep facilities aligned with OSHA expectations and institutional audit requirements for scheduled reference stock.
Procurement: Where to Buy Verified 2F-DCK Standards
Institutional buyers can order the Chem-mist 2F-DCK spray 10% directly through ChemNexis Pharma, with single-unit method-development purchases and bulk wholesale allocations both supported. Every order of Chem-mist 2F-DCK spray 10% is backed by dual-custody chain of custody, batch-specific HRMS confirmation, and discrete trackable global shipping. Compound identity references are maintained in the PubChem compound registry, fragment libraries cross-check against the NIST Chemistry WebBook, and scheduling status is monitored via the DEA Diversion Control Division.
For quotations, technical data sheets, or multi-unit pricing, contact our scientific team, or review validation workflows on our forensic methodology blog. Secure your inventory of Chem-mist 2F-DCK spray 10% today.
Frequently Asked Questions (FAQ)
Q: What is the primary analytical use of the 10% concentration format?
It serves as a lower-concentration liquid calibration standard for GC-MS and LC-MS/MS identification of 2-fluorodeschloroketamine, ideal for trace-level forensic and clinical toxicology matrices.
Q: Does this liquid standard require derivatization for GC-MS?
Yes — like most secondary-amine arylcyclohexylamines, derivatization with MSTFA or TFAA is recommended to improve peak shape and fragmentation.
Q: How many total milligrams are in one unit?
A standard 10 mL pump contains exactly 1,000 mg of 2F-DCK HCl at 10% w/v, delivered across roughly 70 metered actuations of 14 mg each.



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