2F-DCK HCl (2-fluorodeschloroketamine) Reference Standard
The 2F-DCK HCl (2-fluorodeschloroketamine) is a premium analytical reference material engineered for forensic toxicology laboratories and analytical chemists profiling arylcyclohexylamine dissociatives. Formulated as a high-purity crystalline hydrochloride salt (CAS 111982-49-1), this standard provides the exact-mass precision required for rapid calibration of GC-MS and LC-MS/MS instrumentation.
Because arylcyclohexylamines present unique chromatographic challenges, every batch of 2F-DCK HCl (2-fluorodeschloroketamine) ships with comprehensive HPLC purity verification, NMR scaffold confirmation, and HRMS exact-mass documentation, ensuring absolute confidence during method validation and library building.
Chemical Specifications & Arylcyclohexylamine Profiling
2F-DCK belongs to the arylcyclohexylamine class, sharing structural homology with ketamine and deschloroketamine while carrying a fluorine substitution at the 2-position of the phenyl ring. That specific modification shifts both chromatographic retention and mass spectral fragmentation, which is why dedicated reference material is required for confident identification in complex biological matrices.
| Product Name | 2F-DCK HCl (2-fluorodeschloroketamine) |
|---|---|
| Synonym | 2-Fluorodeschloroketamine Hydrochloride |
| CAS Number | 111982-49-1 |
| Molecular Formula | C13H16FNO · HCl |
| Molar Mass | 257.7 g/mol (base) |
| Purity | >98% (HPLC/NMR verified) |
| Format | Crystalline Powder (2g, 5g, 10g, 50g allocations) |
Analytical Applications in Forensic Toxicology
Laboratories deploying 2F-DCK HCl (2-fluorodeschloroketamine) can spike blank urine, blood, and oral-fluid matrices for limit-of-detection (LOD) studies, solid-phase extraction (SPE) recovery testing, and ketamine-analog screening panels. The standard also supports DUID (Driving Under the Influence of Drugs) casework method development and post-mortem redistribution studies where novel dissociatives increasingly appear alongside legacy anesthetics.
By utilizing a verified crystalline format, laboratories can easily perform gravimetric serial dilutions to reach the low ng/mL thresholds required for modern triple-quadrupole mass spectrometers. When your laboratory requires a reliable 2F-DCK HCl (2-fluorodeschloroketamine) standard, ChemNexis Pharma ensures every unit is matched to its batch-specific Certificate of Analysis — explore the full research chemical catalog for companion standards.
Quality Assurance, Storage & Stability
To preserve the >98% purity baseline, 2F-DCK HCl (2-fluorodeschloroketamine) is packaged in light-resistant amber glass with an inert desiccant packet to prevent hydrolytic degradation of the fluorophenyl moiety. Storage protocols specify a cool, dark, desiccated environment (2–8 °C preferred); under these controlled conditions, the certified concentration remains stable for a minimum of 24 months, protecting long-term inventory value for high-volume forensic programs.
Occupational Safety & Handling Protocols
As a concentrated crystalline salt, handling 2F-DCK HCl (2-fluorodeschloroketamine) requires standard laboratory PPE — nitrile gloves, lab coat, and safety goggles — with all weighing and aliquoting performed inside a certified fume hood to prevent aerosol inhalation.
- Inhalation: airborne particulates can cause respiratory irritation; use local exhaust ventilation.
- Skin/Eye Contact: flush immediately with copious water for 15 minutes.
- Environmental: never discharge to municipal water; dispose via licensed hazardous-waste contractors.
These controls keep facilities aligned with OSHA expectations and institutional audit requirements for scheduled reference stock.
Procurement: Where to Buy Verified Arylcyclohexylamine Standards
Institutional buyers can order 2F-DCK HCl (2-fluorodeschloroketamine) directly through ChemNexis Pharma, with single-unit method-development purchases and bulk wholesale allocations both supported. Every order of 2F-DCK HCl (2-fluorodeschloroketamine) is backed by dual-custody chain of custody, batch-specific HRMS confirmation, and discrete trackable global shipping. Compound identity references are maintained in the PubChem compound registry, fragment libraries cross-check against the NIST Chemistry WebBook, and scheduling status is monitored via the DEA Diversion Control Division.
For quotations, technical data sheets, or multi-unit pricing, contact our scientific team, or review validation workflows on our forensic methodology blog. Secure your inventory of 2F-DCK HCl (2-fluorodeschloroketamine) today.
Frequently Asked Questions (FAQ)
Q: What is the primary analytical use of 2F-DCK HCl (2-fluorodeschloroketamine)?
It serves as a gravimetric calibration standard for GC-MS and LC-MS/MS identification of 2-fluorodeschloroketamine in forensic and clinical toxicology matrices.
Q: Does this crystalline standard require derivatization for GC-MS?
Yes — like most secondary-amine arylcyclohexylamines, derivatization with MSTFA or TFAA is highly recommended to improve peak shape, reduce column adsorption, and optimize mass spectral fragmentation.
Q: How should this powder be stored to maintain purity?
Store in the original amber glass vial with desiccant at 2–8 °C, protected from light and moisture, to ensure the >98% purity baseline remains intact for up to 24 months.



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